This session will provide a comprehensive overview of dialysis membrane types and blood purification therapies, highlighting their roles in removing toxins and managing complex clinical conditions. Participants will explore the characteristics and clinical applications of advanced technologies, including medium cut-off dialyzers for enhanced clearance of middle molecules, biofunctional membranes for improved biocompatibility and inflammatory control, and sepsis filters used in critical care settings. Emphasis will be placed on the nursing perspective, with practical guidance on device setup, patient monitoring, interdisciplinary teamwork, and patient education to ensure safe and effective treatment. The session will examine key research findings, such as the CONVINCE trial, and emerging trends in nephrology nursing, empowering nurses to apply evidence-based practices and stay current in this evolving field.