Transitioning into nephrology as a nurse practitioner (NP) requires shifting into the advanced practice role of independently assessing, diagnosing, managing, and treating patients with kidney disease. This session will provide a high-yield, practical overview of how NPs practice across chronic kidney disease management, dialysis care, and hospital nephrology, emphasizing clinical reasoning, medication management, and patient-centered care. For NPs transitioning from dialysis registered nurse roles, the session will clarify how responsibilities expand from executing care plans to developing them. For experienced NPs, it will offer strategies to refine nephrology practice and align with current evidence to improve patient outcomes.