As healthcare organizations navigate the next era of digital transformation, success depends on leadership-driven partnerships between hospitals and technology vendors that are grounded in evidence-based practice. This session explores how hospital–vendor relationships can evolve from transactional engagements into clinical partnerships focused on shared accountability, measurable outcomes, and continuous learning. Attendees will examine best practices for technology evaluation, emphasizing evidence-informed selection criteria such as usability, clinical effectiveness, nurse satisfaction, and alignment with professional practice standards. The discussion will highlight how embedding evidence-based practice into evaluation and governance structures leads to improved adoption and sustained value.